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  1. Chronic short–lasting headaches, in which trigeminal autonomic cephalalgias (TACs) are included, are relatively rare syndromes and not always well recognised. We present a case highly suggestive of short–lasti...

    Authors: M. Guidotti and M. Mauri
    Citation: The Journal of Headache and Pain 2005 6:261
    Content type: Original Published on:

  3. Spontaneous intracranial hypotension is a well defined entity, however it is characterised by a relevant clinical heterogeneity. The main feature is orthostatic headache, often accompanied by other symptoms. T...

    Authors: P. Merlo, A. M. Clerici, B. Stival, V. Rebecchi, M. Noce and S. Mazza
    Citation: The Journal of Headache and Pain 2005 6:258
    Content type: Original Published on:

  6. We describe a woman with a long history of relapsing-remitting painful ophthalmoplegia in a seasonal pattern, due to an isolated orbital myositis that was—at our observation–classified in the context of the so...

    Authors: E. Guaschino, C. Zandrini, G. Minonzio, A. Mancioli, M. Broggini and G. Bono
    Citation: The Journal of Headache and Pain 2005 6:254
    Content type: Original Published on:

  8. This overview of the published epidemiological evidence of migraine helps to identify the size of the public–health problem that migraine represents. It also highlights the need for further epidemiological stu...

    Authors: M. Leonardi, T. J. Steiner, A. T. Scher and R. B. Lipton
    Citation: The Journal of Headache and Pain 2005 6:252
    Content type: Review Published on:

  9. The idea that headache may originate from a problem at the neck or cervical spine level has fascinated and stimulated researchers for centuries. Contributions and reports seeking to clarify this issue have mul...

    Authors: F. Antonaci, G. Bono, M. Mauri, M. Drottning and S. Buscone
    Citation: The Journal of Headache and Pain 2005 6:250
    Content type: HISTORY OF HEADACHE SECTION Published on:

  10. According to an epidemiological study in Japan, there are as many as 22 million patients with tension headache and 8.4 million with migraine. Furthermore, patients suffering from both types of headache concurr...

    Authors: H. Okuma, Y. Kitagawa and S. Takagi
    Citation: The Journal of Headache and Pain 2005 6:249
    Content type: Original Published on:

  11. The objective of this study was to establish if chronic headaches with medication overuse can modify a topo–kinesthetic memory test. Nineteen patients with medication overuse headache (MOH), 13 patients with c...

    Authors: L. A. Pini, G. Guidetti, D. Brovia, P. Pontremoli and P. Sarchielli
    Citation: The Journal of Headache and Pain 2005 6:248
    Content type: Original Published on:

  12. A healthy 22–year–old man complained of primary stabbing headache (PSH) for about two months. The headache recurred after one year and after a month the pain took on the characteristics of short–lasting unilat...

    Authors: F. Raudino
    Citation: The Journal of Headache and Pain 2005 6:246
    Content type: Brief Report Published on:

  13. The basic physiological and anatomical basis for circadian rhythms in mammalian behaviour and physiology is introduced. The pathways involved in photic entrainment of the circadian clock are discussed in relat...

    Authors: M. A. Zordan and C. P. Kyriacou
    Citation: The Journal of Headache and Pain 2005 6:242
    Content type: Erratum Published on:

    The original article was published in The Journal of Headache and Pain 2000 1:Art1

  15. The objective was to evaluate the prevalence and the characteristics of anger and emotional distress in migraine and tension– type headache patients. Two hundred and one headache patients attending the Headach...

    Authors: P. Perozzo, L. Savi, L. Castelli, W. Valfrè, R. Lo Giudice, S. Gentile, I. Rainero and L. Pinessi
    Citation: The Journal of Headache and Pain 2005 6:240
    Content type: Original Published on:

  16. The objective was to evaluate the presence of a positive family history (FH) of vascular risk factors between patients with migraine with aura (MA) and migraine without aura (MO), and in chronic migraine (CM) com...

    Authors: G. Yoon, S. Baggaley, P. Bacchetti, Y.–H. Fu, K. B. Digre and L. J. Ptácek
    Citation: The Journal of Headache and Pain 2005 6:239
    Content type: Brief Report Published on:

  18. In phase one of the REALIZE study, zolmitriptan nasal spray demonstrated a significant headache response from 10 min post–dose and total symptom relief from 30 min post–dose. The objective of phase two was to ...

    Authors: M. Gawel, J. Aschoff, A. May and B. R. Charlesworth
    Citation: The Journal of Headache and Pain 2005 6:237
    Content type: Original Published on:

  19. The characteristics of psychiatric comorbidity in migraine have been studied in migraine with aura (MA) and migraine without aura (MO). Little information is available concerning patients with migraine aura wi...

    Authors: K. J. Oedegaard, J. Angst, D. Neckelmann and O. B. Fasmer
    Citation: The Journal of Headache and Pain 2005 6:236
    Content type: Original Published on:

  20. Post–lumbar puncture headache is a frequent clinical problem. Needle design is expected to reduce post–puncture headache. In this study, we compared two different lumbar puncture needle designs in diagnostic l...

    Authors: L. Luostarinen, T. Heinonen, M. Luostarinen and A. Salmivaara
    Citation: The Journal of Headache and Pain 2005 6:235
    Content type: Original Published on:

  21. Chronic cluster headache remains refractory to medical therapy in at least 30% of those who suffer from this condition. The lack of alternative medical therapies that are as effective as, or more effective tha...

    Authors: P. A. Kowacs, E. J. Piovesan, R. W. G. R. de Campos, M. C. Lange, V. F. Zetola and L. C. Werneck
    Citation: The Journal of Headache and Pain 2005 6:234
    Content type: Brief Report Published on:

  22. The purpose of our study was to prospectively evaluate the impact of preventive drug treatment on the quality of life of patients with episodic migraine (EM). Quality of life evaluations can enhance traditiona...

    Authors: C. A. Bordini, H. Mariano da Silva, R. P. Garbelini, S. O. Teixeira and J. G. Speciali
    Citation: The Journal of Headache and Pain 2005 6:233
    Content type: Original Published on:

  24. In chronic migraine the central sensitisation and the changes of regional cerebral blood flow are mediated by nitric oxide (NO) and oxygen free radicals. Biofeedback is considered a preventive non–pharmacologi...

    Authors: I. Ciancarelli, M. G. Tozzi–Ciancarelli, C. Di Massimo, L. Olivieri and A. Carolei
    Citation: The Journal of Headache and Pain 2005 6:227
    Content type: PREVENTION OF CHRONIC HEADACHES Published on:

  25. Chronic migraine and transformed migraine are conditions with a progression from episodic to chronic headache, a disabling stage. During attack, cutaneous allodynia frequently occurs: it reflects sensitisation...

    Authors: M. Fanciullacci and F. De Cesaris
    Citation: The Journal of Headache and Pain 2005 6:224
    Content type: PREVENTION OF CHRONIC HEADACHES Published on:

  26. We conducted a study on 367 patients (86% female, 14% male; mean age 37±15 years) suffering from migraine with and without aura and chronic tension–type headache to evaluate the incidence of weight gain, an un...

    Authors: F. Maggioni, S. Ruffatti, F. Dainese, F. Mainardi and G. Zanchin
    Citation: The Journal of Headache and Pain 2005 6:221
    Content type: HEADACHE: THERAPEURIC CHOICES Published on:

  27. Sumatriptan is a selective agonist of 5HT1 (1B/1D) receptors, which has proved to be effective and safe for the acute treatment of migraine attacks. Nevertheless, its use by migraine sufferers is still limited...

    Authors: E. Sternieri, D. Pinetti, C. P. R. Coccia, S. Leone, A. Bertolini and A. Ferrari
    Citation: The Journal of Headache and Pain 2005 6:220
    Content type: HEADACHE: THERAPEURIC CHOICES Published on:

  28. The continuous care of headache patients, from headache centres to general practice, is a managerial problem that is still unsolved in Italy. In fact, if on the one hand patients do not usually go to headache ...

    Authors: G. B. La Pegna, F. Brighina, V. Saporito, A. Aloisio, C. Morreale and A. D’Agati
    Citation: The Journal of Headache and Pain 2005 6:217
    Content type: HEADACHE AND CONTINUITY IN HEALTH CARE Published on:

  29. Migraine is a complex pathology and it should be regarded as a disease evolving during the lifetime along with other comorbid conditions. Migraine susceptibility may be unmasked by exogenous substances and the...

    Authors: M. G. Buzzi, D. Cologno and R. Formisano
    Citation: The Journal of Headache and Pain 2005 6:215
    Content type: HEADACHE AND CONTINUITY IN HEALTH CARE Published on:

  30. To evaluate the influence of psychometric variables on the “repeater” phenomenon in an emergency department, 15 “repeaters” and 27 outpatient migraineurs were recruited. All patients were submitted to the Beck...

    Authors: V. Villani, G. Bruti, C. Mostardini, F. Di Stani, L. Scattoni, D. Dugoni, N. Vanacore and R. Cerbo
    Citation: The Journal of Headache and Pain 2005 6:214
    Content type: HEADACHE IN THE EMERGENCY ROOM Published on:

  31. The objective was to study the demographics, diagnostic procedures and therapies employed in order to provide guidelines to Emergency Department (ED) physicians. A six–month retrospective analysis of the recor...

    Authors: G. Relja, A. Granato, F. Capozzoli, C. Maggiore, M. Catalan, G. Pizzolato, W. Zalukar, V. Livia, S. Gregorutti and M. Zorzon
    Citation: The Journal of Headache and Pain 2005 6:213
    Content type: HEADACHE IN THE EMERGENCY ROOM Published on:

  33. The onset of post-traumatic headache occurs frequently in children, where it is often caused by severe head injuries, therefore, it is part of a post–traumatic syndrome, rather than of an independent headache ...

    Authors: D. Moscato, M. I. Peracchi, G. Mazzotta, L. Savi and P. A. Battistella
    Citation: The Journal of Headache and Pain 2005 6:208
    Content type: HEADACHE IN CHILDHOOD AND ADOLESCENCE Published on:

  34. Several epidemiological studies have shown the presence of comorbidity between various types of sleep disorders and different headache subtypes. Migraine without aura is a sensitive risk factor for disorders o...

    Authors: M. Carotenuto, V. Guidetti, F. Ruju, F. Galli, F. R. Tagliente and A. Pascotto
    Citation: The Journal of Headache and Pain 2005 6:204
    Content type: HEADACHE IN CHILDHOOD AND ADOLESCENCE Published on:

  35. The social perception of headache, everywhere at low levels in industrialised countries, becomes totally absent in developing ones. Headache disorders came into the World Health Organization’s strategic priori...

    Authors: P. Martelletti, R. T. Haimanot, M. J. A. Lainez, A. M. Rapoport, K. Ravishankar, F. Sakai, S. D. Silberstein, M. Vincent and T. J. Steiner
    Citation: The Journal of Headache and Pain 2005 6:202
    Content type: HEADACHES, PHYSICIANS AND PATIENTS Published on:

  36. The purpose of this work was to investigate: (1) the differences in temperament and character between 49 women with migraine and 49 controls using the Temperament and Character Inventory (TCI), and (2) the ext...

    Authors: F. Mongini, S. Fassino, E. Rota, A. Deregibus, M. Levi, D. Monticone and G. Abbate–Daga
    Citation: The Journal of Headache and Pain 2005 6:198
    Content type: PSYCHOBIOLOGICAL ASPECTS OF HEADACHES Published on:

  37. Recent investigations documented that the prevalence of right–to–left shunt (RLS) in patients with migraine with aura (MA) is significantly higher than in healthy controls and similar to prevalence of RLS in y...

    Authors: N. Morelli, S. Gori, G. Cafforio, S. Gallerini, F. Baldacci, G. Orlandi and L. Murri
    Citation: The Journal of Headache and Pain 2005 6:197
    Content type: TACs AND CRANIAL NEURALAGIA Published on:

  38. Trigeminal neuralgia is universally considered the neuropathic facial pain most and best known in medical practice. We propose a short review on trigeminal neuralgia reporting its main clinical aspects, unsolv...

    Authors: A. Truini, F. Galeotti and G. Cruccu
    Citation: The Journal of Headache and Pain 2005 6:195
    Content type: TACs AND CRANIAL NEURALAGIA Published on:

  39. Up to a few years ago, cluster headache (CH) was not thought to be an inherited disorder. However, several recent studies have suggested that genetic factors play a role in the disease. Genetic epidemiological...

    Authors: L. Pinessi, I. Rainero, C. Rivoiro, E. Rubino and S. Gallone
    Citation: The Journal of Headache and Pain 2005 6:194
    Content type: TACs AND CRANIAL NEURALAGIA Published on:

  40. The presence of significant and confounding psychiatric comorbidity is greater in patients attending headache clinics than in headache patients from the general population. The frequent comorbidity of headache...

    Authors: M. Savarese, M. Guazzelli, M. P. Prudenzano, M. Carnicelli, M. Rossi, V. Cardinali, S. Genco, P. Lamberti and P. Livrea
    Citation: The Journal of Headache and Pain 2005 6:193
    Content type: HEADACHE: CLINICAL AND COMORBIDITY ASPECTS Published on:

  41. Headache is a frequent feature of functional gastrointestinal disorders but there is no data on the responsible pathophysiological mechanism. The aim of this study was to verify whether alteration of post–pran...

    Authors: E. Pucci, M. Di Stefano, E. Miceli, G. R. Corazza, G. Sandrini and G. Nappi
    Citation: The Journal of Headache and Pain 2005 6:191
    Content type: HEADACHE: CLINICAL AND COMORBIDITY ASPECTS Published on:

  42. This study evaluates osmophobia (defined as an unpleasant perception, during a headache attack, of odours that are non–aversive or even pleasurable outside the attacks) in connection with the diagnosis of prim...

    Authors: G. Zanchin, F. Dainese, F. Mainardi, E. Mampreso, C. Perin and F. Maggioni
    Citation: The Journal of Headache and Pain 2005 6:188
    Content type: ICHD-II EVALUATION AND PROPOSALS Published on:

  43. Medication overuse headache (MOH) is a clinically important entity and it is now well documented that the regular use of acute symptomatic medication by people with migraine or tensiontype headache increases t...

    Authors: P. Calabresi and L. M. Cupini
    Citation: The Journal of Headache and Pain 2005 6:184
    Content type: PATHOPHYSIOLOGY OF HEADACHES Published on:

  44. The study of CNS painmodulating pathways has led to important discoveries about the role of central nociceptive structures such as PAG and hypothalamus in the pathophysiology of episodic and chronic primary he...

    Authors: P. Rossi, M. Serrao, A. Perrotta, F. Pierelli, G. Sandrini and G. Nappi
    Citation: The Journal of Headache and Pain 2005 6:182
    Content type: PATHOPHYSIOLOGY OF HEADACHES Published on:

  45. We examined the distribution of HLA–DRB1 alleles in a cohort of 255 Italian migraine patients and in a control group of 325 healthy subjects. The frequency of DRB1*12 allele was found to be significantly reduced ...

    Authors: I. Rainero, E. Fasano, E. Rubino, C. Rivoiro, W. Valfrè, S. Gallone, L. Savi, S. Gentile, R. Lo Giudice, P. De Martino, A. M. Dall’Omo and L. Pinessi
    Citation: The Journal of Headache and Pain 2005 6:180
    Content type: Genetics Published on:

  46. In the present work, we report that the functional serotonin transporter gene promoter (5–HTTLPR) polymorphism is involved in migraine pathogenesis. The distribution of 5–HTTLPR genotypes was significantly dif...

    Authors: B. Borroni, C. Brambilla, P. Liberini, R. Rao, S. Archetti, S. Gipponi, G. Dalla Volta and A. Padovani
    Citation: The Journal of Headache and Pain 2005 6:179
    Content type: Genetics Published on:

  47. Numerous candidate genes for migraine have been proposed on the basis of their possible functional role in its pathogenesis. Genetic polymorphisms have been evaluated in association studies, some of which have...

    Authors: V. Lisi, G. Garbo, F. Miccichè, A. Stecca, S. Terrazzino, M. Franzoi, E. Tripoli, M. Clementi, A. Leon and P. A. Battistella
    Citation: The Journal of Headache and Pain 2005 6:178
    Content type: Genetics Published on:

  48. Chronic daily headache (CDH) is a heterogeneous group of headaches that includes primary and secondary varieties. Primary CDH is a frequent entity that probably affects 4–5% of the population. It can be subdiv...

    Authors: Miguel J. A. Láinez
    Citation: The Journal of Headache and Pain 2005 6:177
    Content type: KEY NOTE LECTURE Published on:
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