Table 5 Expenditure of preventive drugs dispensed between 2018 and 2022
| Â | 2018 | 2019 | 2020 | 2021 | 2022 | Total | P1 | P2 |
|---|---|---|---|---|---|---|---|---|
Total preventative drugs | 245,363.86 | 281,422.20 | 277,575.91 | 327,095.25 | 320,843.99 | 1,452,301.21 | 0.221 | – |
CCBs | 60,487.77 (24.65) | 72,853.12 (25.89) | 57,446.59 (20.70) | 70,194.61 (21.46) | 57,062.85 (17.79) | 318,044.94 (21.90) | 0.462 | <  0.001 |
 Flunarizine | 59,299.05 (24.17) | 72,853.12 (25.89) | 57,446.59 (20.70) | 70,194.61 (21.46) | 57,062.85 (17.79) | 316,856.22 (21.82) | 0.462 | <  0.001 |
Antidepressants | 101,538.71 (41.38) | 117,488.23 (41.75) | 92,735.89 (33.41) | 107,734.09 (32.94) | 76,892.91 (23.97) | 496,389.83 (34.18) | 0.462 | <  0.001 |
 Flupentixol/melitracen | 23,560.92 (9.60) | 33,441.56 (11.88) | 22,165.50 (7.99) | 30,767.90 (9.41) | 20,623.98 (6.43) | 130,559.86 (8.99) | 0.462 | <  0.001 |
 Amitriptyline | 1395.06 (0.57) | 1405.31 (0.50) | 1602.08 (0.58) | 2759.29 (0.84) | 1232.31 (0.38) | 8394.05 (0.58) | 0.807 | 0.398 |
 Escitalopram | 35,524.44 (14.48) | 36,671.57 (13.03) | 14,199.23 (5.12) | 25,490.65 (7.79) | 16,238.36 (5.06) | 128,124.25 (8.82) | 0.462 | <  0.001 |
Anticonvulsants | 45,860.12 (18.69) | 50,422.43 (17.92) | 58,794.05 (21.18) | 93,473.04 (28.58) | 102,190.54 (31.85) | 350,740.18 (24.15) | 0.028 | <  0.001 |
 Topiramate | 24,308.78 (9.91) | 30,299.16 (10.77) | 40,037.64 (14.42) | 54,532.44 (16.67) | 59,100.48 (18.42) | 208,278.50 (14.34) | 0.028 | <  0.001 |
 Valproate | 11,673.63 (4.76) | 11,790.05 (4.19) | 10,083.37 (3.63) | 18,657.67 (5.70) | 17,593.05 (5.48) | 69,797.77 (4.81) | 0.462 | <  0.001 |
CCMs | 12,529.74 (5.11) | 15,122.32 (5.37) | 20,802.53 (7.49) | 16,278.36 (4.98) | 23,079.52 (7.19) | 87,812.47 (6.05) | 0.086 | <  0.001 |
 Gabapentin | 6346.28 (2.59) | 7883.74 (2.80) | 5711.74 (2.06) | 3468.40 (1.06) | 1703.20 (0.53) | 25,113.36 (1.73) | 0.086 | <  0.001 |
 Pregabalin | 6183.46 (2.52) | 7238.58 (2.57) | 15,090.79 (5.44) | 12,809.96 (3.92) | 21,376.32 (6.66) | 62,699.11 (4.32) | 0.086 | <  0.001 |
Beta blockers | 9643.72 (3.93) | 12,800.38 (4.55) | 12,341.97 (4.45) | 15,395.31 (4.71) | 15,588.51 (4.86) | 65,769.89 (4.53) | 0.086 | <  0.001 |
 Metoprolol | 4679.27 (1.91) | 8064.44 (2.87) | 6384.54 (2.30) | 8162.081 (2.50) | 8946.85 (2.79) | 36,237.18 (2.50) | 0.086 | <  0.001 |
 Propranolol | 1498.06 (0.61) | 1228.10 (0.44) | 1127.36 (0.41) | 1282.85 (0.39) | 1268.64 (0.40) | 6405.01 (0.44) | 0.807 | <  0.001 |
Other agents | 15,303.8 (6.24) | 12,735.72 (4.53) | 35,454.88 (12.77) | 24,019.84 (7.34) | 46,029.66 (14.35) | 133,543.9 (9.20) | 0.221 | <  0.001 |