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Table 5 Comparison of probabilistic and deterministic outcomes over a 5-year horizon

From: An economic evaluation of eptinezumab for the preventive treatment of migraine in the UK, with consideration for natural history and work productivity

Mean outcome

Probabilistic [95% CrI]

Deterministic

Total discounted cost, eptinezumab

£41,270 [£26,272: £57,560]

£41,804

Total discounted cost, BSC

£46,620 [£26,087: £68,770]

£46,698

Discounted QALYs, eptinezumab

2.70 [2.43: 2.98]

2.72

Discounted QALYs, BSC

2.46 [2.07: 2.84]

2.49

Incremental costs

–£5,350 [–£11,647: £503]

–£4,894

Incremental QALYs

0.237 [0.071: 0.436]

0.231

ICER

Dominant in the SE quadrant

Dominant in the SE quadrant

Net monetary benefit @ £20,000

£10,085

£9,515

  1. Abbreviations: BSC Best supportive care, CrI Credible interval, ICER Incremental cost-effectiveness ratio, QALY Quality-adjusted life-year, SE South-east