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Fig. 1 | The Journal of Headache and Pain

Fig. 1

From: AMPK activation attenuates central sensitization in a recurrent nitroglycerin-induced chronic migraine mouse model by promoting microglial M2-type polarization

Fig. 1

Experimental flow chart. a Experiment design for studying the changes in AMP-activated protein kinase (AMPK) activity in the chronic migraine (CM) model mice during the modeling process. b Experimental design to explore the mechanism of AMPK regulating neuroinflammation in CM mice. NTG: nitroglycerin, NS: 0.9% saline, AICAR: AMPK activator 5-aminoimidazole-4-carboxamide1-β-D-ribofuranoside, Compound C: AMPK inhibitor, DMSO: solvent dimethyl sulfoxide, D: day

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