Fig. 5
Anxa10-203 expression was associated with MC1R. a Mc1r expression in the TG on 1, 3, 7, and 14 days after CCI-ION. ***P < 0.001, n = 4/group. b Correlation analysis between Anxa10-203 and Mc1r in the TG by Pearson correlation analysis. R2 = 0.7023, P < 0.0001, n = 20. c Anxa10-203 knockdown reversed the Mc1r mRNA increase induced by CCI-ION. *P < 0.05, **P < 0.01, n = 4/group. d, e Anxa10-203 knockdown reversed the MC1R protein increase induced by CCI-ION. *P < 0.05, n = 4/group. f Anxa10-203 was increased 7 days after LV-Anxa10-203 microinjection in naive mice. *P < 0.05, n = 3/group. g Mc1r mRNA was significantly increased in TG induced by Anxa10-203 over-expression. *P < 0.05, **P < 0.01, n = 3/group. h-i Anxa10-203 over-expression induced increased MC1R protein in naive mice. *P < 0.05, n = 3/group