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Fig. 1 | The Journal of Headache and Pain

Fig. 1

From: LncRNA Anxa10-203 enhances Mc1r mRNA stability to promote neuropathic pain by recruiting DHX30 in the trigeminal ganglion

Fig. 1

Anxa10-203 was up-regulated in the TG after CCI-ION. a Mechanical sensitivity threshold of ipsilateral whisker pad skin in Sham and CCI-ION mice. **P < 0.01, ***P < 0.001, n = 6/group. b, c The expression of the top 10 up-regulated (b) and 10 down-regulated (c) lncRNAs were verified in Sham and CCI-ION mice on day 7 after CCI-ION. *P < 0.05, ***P < 0.001, n = 7/group. d The expression of Anxa10-203 in the TG from mice of Sham and CCI-ION group at days 1, 3, 7, and 14. **P < 0.01, ***P < 0.001, n = 8/group. e The 50% WHT of the ipsilateral whisker pad region was increased in CCI-ION mice with Anxa10-203 silenced in the TG. *P < 0.05, ***P < 0.001, CCI+siAnxa10-203 versus Sham; &&&P < 0.001, CCI+siNC versus Sham; ###P < 0.001, CCI+siAnxa10-203 versus CCI+siNC. n = 5/group. (f) The expression of Anxa10-203 decreased on day 4 after siAnxa10-203 injection. **P < 0.01, ***P < 0.001, n = 3/group

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The Journal of Headache and Pain

ISSN: 1129-2377

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