Table 2 Comparison between M0 (baseline) and M3 (3 months after treatment with MAbs)

Headache days/month, mean (SD)

17.8 (7.4)

10.9 (7.7)

-6.9

 < 0.001

Migraine days/month, mean (SD)

12.7 (7.1)

6.4 (6.1)

-6.3

 < 0.001

Acute medication days/month, mean (SD)

12.2 (6.3)

7.3 (5)

-4.9

 < 0.001

Triptans used/month, mean (SD)

8.4 (6.6)

4.2 (4.6)

-4.2

 < 0.001

MIDAS score, median (Q1-Q3)

50 (95.0–27.8)

14 (45.3–4.0)

-36

 < 0.001

HIT-6 score, median (Q1-Q3)

65 (69.0–61.8)

55.5 (62–48.0)

-9.5

 < 0.001

Total working hours, mean (SD)

37.1 (8.2)

36.5 (8.8)

-0.6

0.347

Absenteeism (%), mean (SD)

13.4 (25.8)

8.4 (21.9)

-5

 < 0.001

Presenteeism (%), mean (SD)

42.7 (29.5)

24.3 (27)

-18.4

 < 0.001