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Table 4 Safety outcomes

From: Real-world effectiveness of Anti-CGRP monoclonal antibodies compared to OnabotulinumtoxinA (RAMO) in chronic migraine: a retrospective, observational, multicenter, cohort study

 

Anti-CGRP mAbs

(n = 86)

BoNT-A

(n = 97)

p-value

SAE, n (%)

0 (0.0)

0 (0.0)

-

Discontinuation due to AE, n (%)

1 (1.2)

0 (0.0)

0.470

Arthralgia

1 (1.2)

0 (0.0)

-

Discontinuation due to other reasons, n (%)

10 (11.6)

20 (20.6)

0.113

Inefficacy

10 (11.6)

12 (12.4)

-

Injection procedure not tolerated

0 (0.0)

3 (3.1)

-

Psychiatric concomitant conditions

0 (0.0)

1 (1.0)

-

Pregnancy

0 (0.0)

1 (1.0)

-

Surgery

0 (0.0)

1 (1.0)

-

Patient moved

0 (0.0)

1 (1.0)

 
  1. Abbreviations: AE Adverse events, BoNT-A Onabotulinumtoxin-A, CGRP Calcitonin gene related peptide, mAbs Monoclonal antibodies, SAE Serious adverse events