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Table 1 Sex-specific releative changes in capsaicin-stimulated CGRP and substance P release

From: Anti-CGRP antibody galcanezumab modifies the function of the trigeminovascular nocisensor complex in the rat

 

Stimulated CGRP release

Stimulated substance P release

Sex

Males

Females

Males

Females

Treatment group

Vehicle (n = 14)

Galcan. (n = 6)

Vehicle (n = 10)

Galcan (n = 26)

Vehicle (n = 14)

Galcan. (n = 10)

Vehicle (n = 6)

Galcan. (n = 26)

Mean (%)

212.19

233.89

257.39

173.10

72.30

95.99

47.96

101.86

SEM (%)

18.32

17.45

13.81

6.81

7.84

5.18

12.22

10.80

PHSD

0.858

 < 0.005

0.770

 < 0.05

  1. PHSD values are from unequal N honest significance post-hoc test following factorial ANOVA with factors treatment and sex. Galcan. Galcanezumab