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Fig. 5 | The Journal of Headache and Pain

Fig. 5

From: Involvement of the ipsilateral-to-the-pain anterior–superior hypothalamic subunit in chronic cluster headache

Fig. 5

ROI-to-ROI functional connectivity from 166 healthy individuals of the 7 T Human Connectome Project (HCP) rs-fMRI dataset for the anterior–superior hypothalamic sub-unit within the areas/structures of the mesocorticolimbic system. Results are significant for parametric multivariate statistics (cluster threshold: p < 0.05 cluster-level, p-FDR corrected—MVPA omnibus test; connection threshold: p < 0.05 uncorrected). Abbreviations: hyp ANT-SUP = anterior–superior hypothalamic sub-unit, Medial PFC = medial prefrontal cortex, AMY = amygdala, HIPP = hippocampus, F.Orb. = frontal orbital, F Pole = frontal pole, VTA = ventral tegmental area, Nacc = nucleus accumbens, R = right, L = left

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