Fig. 6
From: Tryptophan metabolites and gut microbiota play an important role in pediatric migraine diagnosis
Logistic regression analysis of the association between tryptophan metabolites and pediatric migraine. The forest plot depicts log odds ratios (ORs) for tryptophan metabolites. On the right side, raw ORs and 95% CI for tryptophan metabolites are presented. A The OR values and 95% CI obtained from univariate binary logistic regression are displayed. Kynurenic acid (KYNA), kynurenine (KYN), the ratio of kynurenine to tryptophan (KYN/TRP), the ratio of kynurenic acid to kynurenine (KYNA/KYN), and the ratio of kynurenic acid to quinolinic acid (KYNA/QUIN) emerge as protective factors against pediatric migraine. Conversely, tryptophan (TRP), serotonin (5-HT), quinolinic acid (QUIN), the ratio of quinolinic acid to kynurenine (QUIN/KYN), and age are identified as risk factors for pediatric migraine. Sex may not be significantly associated with pediatric migraine. B The OR values and 95% CI for tryptophan metabolites from multivariable logistic regression reveal that tryptophan (TRP), quinolinic acid (QUIN), and serotonin (5-HT) are risk factors for pediatric migraine, while kynurenine (KYN), kynurenic acid (KYNA), and quinolinic acid (QUIN) serve as protective factors. Age may not be significantly associated with pediatric migraine