Fig. 5

NF-κB inhibition results in downregulation of c-fos and CGRP expression. a, b Immunoblot analysis of p-p65 to p65 ratio and p-IκBα to IκBα ratio was conducted in the indicated groups (n=6). c-f Immunoblot analysis of c-fos and CGRP was conducted (n=6). g, h Quantification of CGRP immunoreactivity was conducted (n=5). Three slices were taken from each mouse for analysis. Values are the mean±SEM; one-way ANOVA and Tukey's post hoc tests; ***p < 0.001 vs. the VEH group; ^##p < 0.01 and ^###p < 0.001 vs. the NTG group; ^&&p < 0.01 vs. the VEH-LR12 group.