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Fig. 3 | The Journal of Headache and Pain

Fig. 3

From: Microglia TREM1-mediated neuroinflammation contributes to central sensitization via the NF-κB pathway in a chronic migraine model

Fig. 3

TREM1 blockade results in downregulation of c-fos and CGRP expression. a-d Immunoblot analysis of TREM1, c-fos, and CGRP (n=6). e, f Quantification of CGRP immunoreactivity (n=5). Scale bars: 100 μm; each mouse was selected for three slices for analysis. Values are presented as the mean ± SEM; one-way ANOVA and Tukey's post hoc tests; ***p < 0.001 vs. the VEH group; ###p < 0.001 vs. the NTG group

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