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Table 1 Parameters of dc potential shifts associated with SD in awake and anesthetized rats

From: Different vulnerability of fast and slow cortical oscillations to suppressive effect of spreading depolarization: state-dependent features potentially relevant to pathogenesis of migraine aura

Cortical region

SD latency (s)

SD duration (s)

SD amplitude (mV)

Awake rats (n = 7)

 Frontal cortex

169 ± 7

45 ± 2

8.0 ± 0.7

 Occipital cortex

160 ± 5

41 ± 2

6.1 ± 0.7

Anesthetized rats (n = 6)

 Frontal cortex

200 ± 5*

63 ± 3*

8.7 ± 0.3

 Occipital cortex

220 ± 20*

57 ± 3*

5.8 ± 1.2

  1. *-significant difference between awake and anesthetized rats (p < 0.05, Mann–Whitney test)