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Fig. 3 | The Journal of Headache and Pain

Fig. 3

From: Different vulnerability of fast and slow cortical oscillations to suppressive effect of spreading depolarization: state-dependent features potentially relevant to pathogenesis of migraine aura

Fig. 3

Depression of spontaneous cortical activity induced by unilateral SD in urethane-anesthetized rats. Typical recordings of dc potential (A), filtered ECoG (B) and spectrogram (C) of the 800-s fragment obtained in homotopic sites of the right (Cx, R) and left (Cx, L) occipital cortex of the two hemispheres immediately after a focal microinjury of the right amygdala (marked by red dashed line at the onset of recordings) in the rat shown in Fig. 2 under awake conditions. Calibration bars – 2 mV (A) and 0.2 mV (B). The time scale is the same in A, B, C and shown below the spectrogram. A single SD event (dc shift) appeared in the right occipital cortex in 220 s after its initiation in the amygdala (A) and induced pronounced ECoG flattering in the ipsilateral cortex (B, C)

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