Association of intradialysis blood sodium level, blood pressure variability, and hydration status with hemodialysis-related headache: a prospective cohort study

Table 3 Risk factors for hemodialysis-related headache in logistic regression analysis

Variable	OR (univariate)	95%CI (univariate)	P value (univariate)	OR (multivariate)	95%CI (multivariate)	P value (multivariate)
Age (/1 year)	0.958	0.918–1.000	0.049	0.844	0.719–0.991	0.039
URR (/1%)	1.034	0.964–1.110	0.347	1.139	0.969–1.339	0.114
Dialysis vintage (/1 month)	0.992	0.959–1.027	0.644	0.980	0.927–1.036	0.485
Pulse-ARV (/1%)	1.141	0.671–1.941	0.627	1.279	0.471–3.473	0.629
SBP-ARV (/1 point)	1.114	0.824–1.505	0.483	3.067	1.006–9.348	0.049
DBP-ARV (/1 point)	1.105	0.707–1.728	0.660	0.479	0.178–1.294	0.147
SpO2%-ARV (/1 point)	< .001	< .001–0.660	0.038	< .001	< .001–12.901	0.140
pH (/1%)	1.017	0.873–1.184	0.829	4.463	0.648–30.718	0.129
pCO2 (/1 mmHg)	1.027	0.885–1.192	0.726	3.649	0.712–18.709	0.121
Base excess (/1 mmol/L)	1.141	0.761–1.710	0.523	0.045	0.002–1.252	0.068
HCO3- (/1 mmol/L)	1.116	0.855–1.455	0.420	2.245	0.805–6.260	0.122
Sodium (/1 mmol/L)	0.762	0.516–1.127	0.174	0.309	0.111–0.856	0.024
\|OH/DW\|^a (/1%)	1.373	0.989–1.905	0.058	1.990	1.033–3.832	0.040
Constant				< .001		0.163

Abbreviations: OR odd ratio, CI confidence interval, URR urea reduction ratio, ARV average real variability, SBP systolic blood pressure, DBP diastolic blood pressure, pCO2 partial pressure of carbon dioxide, OH overhydration, DW dry weight. The dependent variable was defined as a patient having HRH. For multivariate logistic regression analysis: Hosmer–Lemeshow χ2 = 4.255, p = 0.833; percentage correct 96.7%
^aAbsolute value of the ratio of overhydration volume (in litres) to dry weight (in kilograms), which reflects the degree of hydration imbalance

ISSN: 1129-2377