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Table 1 The demographics and the headache profiles of RCVS patients

From: Association between impaired dynamic cerebral autoregulation and BBB disruption in reversible cerebral vasoconstriction syndrome

 

RCVS

BBB disruption

No BBB disruption

p

N

45

19

26

-

Age (yr), mean ± SD

41.9 ± 9.8

46.3 ± 9.9

38.7 ± 8.5

0.009*

male, n (%)

16 (36)

6 (32)

10 (38)

0.634

Hypertension, n (%)

5 (11)

4 (21)

1 (4)

0.146a

migraine, n (%)

13 (29)

9 (47)

4 (15)

0.043*a

menopause, n (%), female only

12 (41)

10 (77)

2 (13)

0.001*a

smoking, n (%)

16 (36)

7 (37)

9 (35)

0.878

BP surge, n (%)

5 (11)

3 (16)

2 (8)

0.636a

potential secondary cause, n (%)

5 (11)

1 (5)

4 (15)

0.378a

Headache triggers

 bathing/showering, n (%)

10 (22)

4 (21)

6 (23)

1.000a

 exertion, n (%)

17 (38)

9 (47)

8 (31)

0.257

 Valsalva, n (%)

27 (60)

14 (74)

13 (50)

0.109

 emotion, n (%)

11 (24)

5 (26)

6 (23)

0.803

 sexual activity, n (%)

22 (49)

8 (42)

14 (54)

0.436

  1. Data presented as mean ± standard deviation. a calculated with Fisher’s exact test. * p < 0.05
  2. Potential secondary causes: exposure to illicit and vasoactive agents, postpartum status, exposure to female reproductive hormonal treatment, and acute food poisoning with violent vomiting preceding RCVS onset
  3. BBB Blood-brain barrier, BP Blood pressure, RCVS Reversible cerebral vasoconstriction syndrome