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Table 2 Resource use and unit costs

From: Competing treatments for migraine: a headache for decision-makers

Resource use item

Unit cost

Source

Prophylactic drugs (3 monthly cycle) – 2022 prices

 BTAc

£276.40

https://bnf.nice.org.uk/ [32]

 Eptinezumabc 100mg

£1,350.00

 Eptinezumabc 300mg

£4,050.00

 Fremanezumab—monthly

£1,350.00

 Fremanezumab—quarterly

£1,350.00

 Galcanezumab

£1,350.00a

 Topiramate

£5.10

Staff time in 2021/2022 prices

 Nurse (hourly cost)

£42.00

Unit Costs of Health and Social Care, 2021 [35]

 Specialist consultant – neurologist (hourly cost)

£122.00b

Latest tariff did not include costs for neurology outpatient therefore assumed to be a Follow Up Attendance—Single Professional (WF01A) for a Neurology outpatient visits (code 400) [36]

Other resource items in 2021/2022 prices

 GP visit

£39.23

Unit Costs of Health and Social Care, 2021 [35]

 A&E visit

£165.00

A&E worksheet. 'VB08Z', Emergency Medicine, Category 2 Investigation with Category 1 Treatment [37]

 Hospital admission

£618.00

Non-elective tariff for code AA31E (Headache, Migraine or Cerebrospinal Fluid Leak, with CC Score 0–6) in worksheet “1 APC & OPROC” HRG code: AA31E [37]

 Triptan usage

£3.99

The cost of triptans per attack was based on the weighted average of triptan costs in the UK, taken from NHS Prescriptions Cost Analysis [18, 25]

  1. aThe cost of maintenance dose in each subsequent cycle
  2. bUprated to 2021/2022 prices
  3. cDrugs administered in hospital