Table 4 Monthly migriane days (MMDs), monthly headache days (MHDs) and HIT6-score (HIT) at M0, M3, M6, M9 and M12 with change from baseline (BL or M0) at M3, M6, M9 and M12

Patients (n)

140

140

118

107

102

MHDs

22.5 ± 7.3

14.5 ± 9.6^a

13.4 ± 9.0^a

12.2 ± 8.6^a

11.9 ± 8.7^a

 Change from BL

-

8.0 ± 7.1

8.6 ± 7.4

9.4 ± 8.5

9.8 ± 7.8

MMDs

19.6 ± 7.4

11.5 ± 8.5^a

10.0 ± 6.8^a

9.2 ± 6.1^a

9.0 ± 6.3^a

 Change from BL

-

8.1 ± 5.9

8.8 ± 6.1

9.1 ± 6.5

9.2 ± 5.7

HIT

68.0 ± 6.0

59.3 ± 8.1^a

57.0 ± 8.9^a

56.5 ± 9.9^a

56.5 ± 9.0^a

 Change from BL

-

8.8 ± 7.7

10.9 ± 8.8

11.3 ± 9.6

11.1 ± 8.6