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Table 1 Comparison of baseline data between training and validation sets

From: Development and validation of non-invasive prediction models for migraine in Chinese adults

Variable

Training set

Validation set

P1

P2

P3

Total(N = 188)

Control(N = 60)

Migraine(N = 128)

Total(N = 94)

Control(N = 30)

Migraine(N = 64)

Gender, male, n(%)

27(14.36)

10(16.67)

17(13.28)

17(18.09)

5(16.67)

12(18.75)

0.537

0.807

0.417

Gender, female, n(%)

161(85.64)

50(83.33)

111(86.72)

77(81.91)

25(83.33)

52(81.25)

Age, years, median[IQR]

35.00[31.00,41.00]

34.00[29.00,37.00]

36.00[31.00,42.00]

37.00[32.00,43.00]

37.00[33.00,45.00]

38.00[32.00,42.00]

0.164

0.742

0.096

BMI, kg/m2, median[IQR]

21.88[19.83,22.99]

22.01[19.88,23.56]

21.23[19.81,22.76]

21.51[19.59,23.95]

21.27[19.24,22.83]

21.83[20.07,24.22]

0.392

0.316

0.366

Smoking history, n(%)

18(9.57)

4(6.67)

14(10.94)

10(10.64)

1(3.33)

9(14.06)

0.354

0.116

0.778

Drinking history, n(%)

39(20.74)

11(18.33)

28(21.88)

19(20.21)

6(20.00)

13(20.31)

0.577

0.972

0.917

Weekly exercise time, hours, median[IQR]

0.00[0.00,1.00]

0.00[0.00,0.67]

0.00[0.00,1.50]

0.00[0.00,1.33]

0.00[0.00,2.00]

0.00[0.00,1.17]

0.077

0.680

0.817

Pressure score, mean(± SD)

5.10 ± 2.46

5.49 ± 2.37

4.93 ± 2.49

5.26 ± 2.37

4.93 ± 2.46

5.40 ± 2.32

0.154

0.387

0.624

PSQI score, median[IQR]

6.00[4.00,8.00]

4.00[3.00,5.00]

7.00[5.00,9.00]

5.00[4.00,8.00]

4.00[3.00,5.00]

7.00[4.00,9.00]

 < 0.001

 < 0.001

0.199

SAS score, median[IQR]

38.75[33.75,46.25]

33.75[31.25,37.50]

42.50[36.25,48.75]

38.75[32.50,46.25]

33.75[30.00,40.00]

42.50[35.00,47.50]

 < 0.001

 < 0.001

0.799

SDS score, median[IQR]

38.75[33.75,48.75]

37.50[33.75,41.25]

40.00[33.75,51.25]

38.75[32.50,50.00]

33.75[28.75,42.50]

41.25[35.00,52.50]

0.017

 < 0.001

0.888

TCMC score

 Gentleness score, mean(± SD)

62.42 ± 18.29

70.73 ± 15.88

58.52 ± 18.05

62.27 ± 19.27

73.86 ± 16.99

56.84 ± 17.81

 < 0.001

 < 0.001

0.942

 Qi-deficiency score, median[IQR]

25.00[15.63,40.63]

18.75[9.38,21.88]

31.25[18.75,46.88]

25.00[15.63,37.50]

18.75[3.13,28.13]

28.13[21.88,40.63]

 < 0.001

 < 0.001

0.642

 Yang-deficiency score, median[IQR]

28.13[10.71,46.43]

15.63[3.13,32.14]

28.57[14.29,50.00]

25.00[10.71,42.86]

15.63[7.14,28.13]

32.14[14.29,53.57]

0.004

0.002

0.951

 Yin-deficiency score, median[IQR]

21.88[9.38,34.38]

18.75[9.38,31.25]

21.88[12.50,34.38]

25.00[6.25,37.50]

15.63[6.25,31.25]

28.13[9.38,40.63]

0.128

0.066

0.985

 Phlegm-wetness score, median[IQR]

25.00[12.50,40.63]

25.00[12.50,43.75]

25.00[15.63,40.63]

25.00[12.50,40.63]

25.00[12.50,34.38]

25.00[12.50,43.75]

0.598

0.503

0.968

 Wet-heat score, median[IQR]

25.00[12.50,45.83]

25.00[12.50,45.83]

29.17[16.67,41.67]

25.00[12.50,41.67]

29.17[16.67,45.83]

25.00[12.50,41.67]

0.635

0.542

0.949

 Blood-stasis score, median[IQR]

25.00[10.71,35.71]

17.86[7.14,25.00]

28.57[17.86,39.29]

21.43[10.71,32.14]

14.29[10.71,25.00]

25.00[10.71,35.71]

 < 0.001

0.026

0.308

 Qi-depression score, median[IQR]

21.43[7.14,42.86]

7.14[3.57,21.43]

28.57[10.71,42.86]

21.43[7.14,35.71]

7.14[3.57,17.86]

32.14[14.29,39.29]

 < 0.001

 < 0.001

0.915

 Special diathesis score, median[IQR]

17.86[7.14,32.14]

17.86[14.29,32.14]

17.86[7.14,32.14]

17.86[7.14,32.14]

14.29[7.14,21.43]

17.86[7.14,32.14]

0.300

0.240

0.511

  1. P1 indicated the comparison between the migraine group and the control group in the training set; P2 indicated the comparison between the migraine group and the control group in the validation set; P3 indicated the comparison of the total samples between the training and validation sets.Chi-squared test, t test and Mann–whitney U test were used for statistical analysis, which were expressed as n (%), mean (± SD), and medium [IQR], respectively. SD Standard deviation, IQR Interquartile range, BMI Body mass index, PSQI Pittsburgh sleep quality index, SAS Self-rating anxiety scale, SDS Self-rating depression scale, TCMC Traditional Chinese medicine constitution