Skip to main content
Fig. 4 | The Journal of Headache and Pain

Fig. 4

From: Medication overuse headache is associated with elevated lipopolysaccharide binding protein and pro-inflammatory molecules in the bloodstream

Fig. 4

Serum levels of circulating biomarkers of leaky gut, inflammation and pain in female Sprague Dawley rats exposed to chronic piroxicam (MOH) or vehicle (Control). Compared to the control group, serum levels of A CGRP, B LBP, C occludin, D VE-cadherin, E IL-6 and F IL-17 levels were significantly higher in MOH group compared to the control group. Data were shown as mean ± SD. Statistical analysis was performed with student t-test for CGRP, LBP and occludin and Mann–Whitney’s U test for VE-cadherin, IL-6 and IL-17

Back to article page

The Journal of Headache and Pain

ISSN: 1129-2377

Contact us