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Table 2 Demographic and clinical characteristics for the Application Dataset and the External Validation Dataset. Not all patients completed the headache diary. Complete data was available from 87 EM patients and 72 CM patients

From: Increased MRI-based Brain Age in chronic migraine patients

 

NKI-RS (n=144)

HC (n=82)

EM (n=91)

CM (n=74)

Statistical Test

Woman \(N^{\underline{\circ }}\). (%)

89 (61.8 %)

68 (82.9 %)

75 (82.4 %)

68 (91.9 %)

sex - \(\chi ^2\) = 3.56, P = 0.17a  

Age, y

35.5 ± 12.0

35.7 ± 12.0

36.4 ± 9.9

37.8 ± 9.7

age - ANOVA = 0.86, P = 0.43b

EM n = 87; CM n = 72;

     Duration of migraine history, y

  

14.1 ± 10.7

19.8 ± 10.7

t = -3.32, P = 0.001c 

     Duration of Chronic migraine, mo

   

28.4 ± 35.3

 

     Headache frequency d/mo

  

3.5 ± 2.1

23.5 ± 6.0

U = 66, P < 0.001d

     Migraine frequency d/mo

  

3.6 ± 2.0

13.6 ± 6.8

U = 225.5, P < 0.001d

  1. Data expressed as mean ± SD
  2. aChi-square test
  3. bANOVA
  4. cTwo-tailed, unpaired Student t test
  5. dMann-Whitney U test