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Table 1 Demographic and clinical characteristics among HC, EM, and CM

From: Hyperperfusion of bilateral amygdala in patients with chronic migraine: an arterial spin-labeled magnetic resonance imaging study

 

HC (n = 26)

EM (n = 26)

CM (n = 55)

P value

Age (years)

41.50 (31.75–46.25)

39.50 (32.00–46.50)

46.00 (33.75–52.00)

0.201

Female, n (%)

19 (73.1)

19 (73.1)

43 (78.2)

0.828

BMI (kg/m2)

22.72 (20.05–25.00)

22.82 (21.10–26.15)

22.87 (20.94–25.41)

0.723

Right-handers, n (%)

26 (100.0)

26 (100.0)

55 (100.0)

1.000

Unilateral headache, n (%)

NA

10 (38.5)

25 (45.5)

0.553

Disease duration (years)

NA

15.48 ± 10.00

21.00 ± 10.67

0.025*

Headache frequency, days/month

NA

8.00 (4.00–12.75)

25.00 (15.00–30.00)

 < 0.001***

Headache intensitya

NA

7.00 (6.25–8.00)

7.00 (6.00–9.00)

0.221

MIDAs score (0–270)

NA

50.00 (18.00–70.00)

100.00 (59.00–179.00)

 < 0.001***

HIT-6 score (36–78)

NA

64.00 (59.25–68.75)

66.00 (64.00–71.75)

0.090

PHQ-9 score (0–27)

NA

4.00 (1.00–7.00)

8.50 (3.75–16.00)

0.001**

GAD-7 score (0–21)

NA

2.00 (1.00–4.50)

6.00 (2.00–13.25)

0.005**

PSQI score (0–21)

NA

8.30 ± 4.54

10.15 ± 4.67

0.122

  1. HC healthy control, EM episodic migraine, CM chronic migraine, BMI body mass index, MIDAs Migraine Disability Assessment Scale, HIT-6 Headache Impact Test-6, PHQ-9 Patient Health Questionnaire-9, GAD-7 Generalized Anxiety Disorder-7, PSQI Pittsburgh Sleep Quality Index
  2. *P < 0.05
  3. **P < 0.01
  4. ***P < 0.001
  5. aHeadache intensity on a 0–10 numerical rating scale