Fig. 1

Post-processing diagram of cerebral perfusion by multi-delay ASL MR imaging in bilateral amygdala. Firstly, the 3D T1 image was respectively co-registered to the arrival-time-corrected cerebral blood flow (CBF) and arterial transit time (ATT) maps. Then the CBF and ATT maps were linearly co-registered in the native space to their corresponding 3D T1WI images, which were non-linearly registered to the standard Montreal Neurologic Institute (MNI) stereotaxic space. Finally, the co-registered CBF and ATT images were generated. The ROI mask of the amygdala was generated by the automatic anatomical labeling atlas 3 (AAL3) template. The CBF and ATT values of amygdala were extracted from the registered CBF and ATT images based on the amygdala mask