Fig. 4

Optogenetic CSDs cause a prolonged impairment of nest building behaviour in both WT and FHM1 mutant mice. Nest building behaviour was impaired at 24 h, and had still not normalized at 48 h, after optogenetically induced CSDs in both genotypes, with no genotypic difference, and had even not returned to baseline at the 72-h time point. * p < 0.05, ** p < 0.01, *** = p < 0.001. Black asterisks and brackets: uncorrected p-values. Grey symbols: corrected p-values (after Kruskall-Wallis; see Results text for number and nature of corrections)