Migraine cohort | 0–3 HD/m (n = 13,759) | 4–7 HD/m (n = 4203) | 8–14 HD/m (n = 1730) | ≥ 15 HD/m (n = 1064) | Total (N = 20,756) |
---|---|---|---|---|---|
Age (years), mean (SD) | 40.1 (13.5) | 40.7 (13.3) | 41.2 (13.5) | 42.2 (13.9) | 40.4 (13.5) |
Sex (female), n (%) | 7846 (57.0) | 2717 (64.6) | 1177 (68.0) | 772 (72.6) | 12,512 (60.3) |
Marital status, n (%) | |||||
Married or living with partner | 8972 (65.2) | 2831 (67.4) | 1144 (66.1) | 664 (62.4) | 13,611 (65.6) |
Single, separated, divorced or widowed | 4697 (34.1) | 1340 (31.9) | 580 (33.5) | 393 (36.9) | 7010 (33.8) |
Prefer not to answer | 90 (0.7) | 32 (0.8) | 6 (0.3) | 7 (0.7) | 135 (0.7) |
Employment status, n (%) | |||||
Employed full or part time | 9815 (71.3) | 3023 (71.9) | 1163 (67.2) | 619 (58.2) | 14,620 (70.4) |
Not employeda | 3834 (27.9) | 1147 (27.3) | 557 (32.2) | 429 (40.2) | 5967 (28.7) |
Prefer not to answer | 110 (0.8) | 33 (0.8) | 10 (0.6) | 16 (1.5) | 169 (0.8) |
Previously diagnosed with migraine by healthcare provider, n (%) | 7269 (52.8) | 2805 (66.7) | 1169 (67.6) | 705 (66.3) | 11,948 (57.6) |
Age at migraine diagnosis,b mean (SD) | 24.0 (10.6) | 24.4 (11.0) | 25.1 (11.0) | 24.3 (11.6) | 24.2 (10.8) |
HD/m, mean (SD) | 1.8 (1.0) | 5.4 (1.0) | 10.3 (1.7) | 20.8 (4.8) | 4.2 (4.9) |
Number of comorbidities (excluding migraine), n (%) | |||||
1 | 3667 (26.7) | 866 (20.6) | 326 (18.8) | 156 (14.7) | 5015 (24.2) |
2 | 2716 (19.7) | 772 (18.4) | 324 (18.7) | 145 (13.6) | 3957 (19.1) |
3 + | 4305 (31.3) | 1868 (44.4) | 881 (50.9) | 666 (62.6) | 7720 (37.2) |
MIDAS grade,c n (%) | |||||
I – little or no disability | 6689 (48.6) | 1043 (24.8) | 291 (16.8) | 154 (14.5) | 8177 (39.4) |
II – mild disability | 2988 (21.7) | 728 (17.3) | 180 (10.4) | 80 (7.5) | 3976 (19.2) |
III – moderate disability | 2438 (17.7) | 1036 (24.6) | 382 (22.1) | 148 (13.9) | 4004 (19.3) |
IV – severe disability | 1644 (11.9) | 1396 (33.2) | 877 (50.7) | 682 (64.1) | 4599 (22.2) |
MIBS-4 total score,d n (%) | |||||
0 – no interictal burden | 4223 (30.7) | 919 (21.9) | 345 (19.9) | 159 (14.9) | 5646 (27.2) |
1–2 – mild interictal burden | 2156 (15.7) | 642 (15.3) | 242 (14.0) | 143 (13.4) | 3183 (15.3) |
3–4 moderate interictal burden | 1714 (12.5) | 543 (12.9) | 213 (12.3) | 147 (13.8) | 2617 (12.6) |
5 + – severe interictal burden | 5666 (41.2) | 2099 (49.9) | 930 (53.8) | 615 (57.8) | 9310 (44.9) |
MSQ v2.1 score,e mean (SD) | |||||
Role function – restrictive | 67.2 (21.3) | 56.6 (19.2) | 53.1 (19.6) | 47.5 (21.5) | 62.9 (21.8) |
Role function – preventive | 74.9 (22.9) | 67.8 (22.9) | 64.8 (23.5) | 60.9 (25.5) | 71.9 (23.5) |
Role function – emotional function | 74.6 (24.1) | 65.4 (24.5) | 61.2 (25.4) | 55.1 (27.3) | 70.6 (25.2) |