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Table 4 Statistically significant cortical thickness differences between healthy controls and migraine subgroups (CM and EM)

From: Cortical metabolic and structural differences in patients with chronic migraine. An exploratory 18FDG-PET and MRI study

Anatomical Areas, mean (SD)

HC

(N = 10)

EM

(N = 8)

CM

(N = 7)

Adj. P Value

HC

(N = 10)

EM

(N = 8)

CM

(N = 7)

Adj. P Value

HC-EM

HC-CM

EM-CM

HC-EM

HC-CM

EM-CM

LEFT side

RIGHT side

Frontal Areas

            

 Caudal Middle Frontal

2.480 (0.054)

2.481 (0.063)

2.608 (0.069)

0.986

0.028

0.043

2.414 (0.067)

2.473 (0.080)

2.578 (0.080)

0.389

0.040

0.138

 Medial Orbitofrontal

2.317 (0.067)

2.378 (0.057)

2.472 (0.072)

0.377

0.025

0.093

2.330 (0.049)

2.305 (0.059)

2.367 (0.062)

0.748

0.642

0.480

 Pars Opercularis

2.540 (0.040)

2.596 (0.048)

2.609 (0.041)

0.386

0.302

0.857

2.638 (0.039)

2.469 (0.047)

2.604 (0.050)

0.011

0.587

0.064

 Rostral Middle Frontal

2.305 (0.043)

2.287 (0.050)

2.415 (0.054)

0.688

0.022

0.016

2.186 (0.044)

2.217 (0.054)

2.316 (0.058)

0.508

0.022

0.052

 Superior Frontal

2.673 (0.052)

2.684 (0.062)

2.793 (0.067)

0.836

0.028

0.062

2.630 (0.031)

2.577 (0.037)

2.707 (0.039)

0.286

0.136

0.026

Temporal areas

            

 Transverse Temporal

2.451 (0.067)

2.291 (0.080)

2.469 (0.085)

0.141

0.868

0.146

2.506 (0.058)

2.318 (0.069)

2.435 (0.073)

0.049

0.460

0.260

 Parahippocampal

2.892 (0.087)

2.776 (0.104)

2.693 (0.110)

0.405

0.172

0.595

2.944 (0.100)

2.777 (0.115)

2.705 (0.122)

0.080

0.018

0.488

 Temporal Pole

3.717 (0.082)

3.620 (0.098)

3.720 (0.104)

0.459

0.983

0.498

4.021 (0.086)

3.677 (0.103)

3.997 (0.100)

0.018

0.863

0.057

Parietal Areas

            

 Inferior Parietal

2.414 (0.034)

2.441 (0.040)

2.478 (0.043)

0.625

0.252

0.530

2.452 (0.050)

2.465 (0.060)

2.559 (0.052)

0.787

0.048

0.108

  1. Bold font in the P values column indicates statistically significant
  2. Significance assessed with ANCOVA modelling adjusted by patients’ age in order to find cortical thickness differences between healthy controls and migraine patients (EM and CM)
  3. HC healthy controls; EM episodic migraine; CM chronic migraine; SD standard deviation; Adj. P value adjusted P value (Bonferroni correction)