Table 6 HRQoL scores (mean and 95% CI) for males^a and females^b with recurrent headache and associated conditions, compared to a healthy group, collapsed across cohorts

Physical functioning

10–11

82.5 (81.5, 83.5)

74.0 (69.4, 78.5)

< 0.001

81.5 (80.4, 82.5)

76.1 (70.8, 81.5)

0.06

12–13

85.2 (84.3, 86.1)

77.1 (73.2, 80.9)

< 0.001

85.1 (84.2, 86.0)

76.7 (73.2, 80.1)

< 0.001

14–15

83.9 (82.2, 85.6)

67.9 (58.5, 77.3)

0.001

82.3 (80.7, 83.8)

71.9 (66.0, 77.8)

< 0.001

16–17

85.1 (83.2, 87.0)

78.4 (73.6, 83.2)

0.013

82.9 (81.2, 84.6)

75.5 (71.3, 79.6)

0.002

Emotional functioning

10–11

77.0 (76.2, 77.8)

67.7 (63.5, 71.9)

< 0.001

76.5 (75.7, 77.3)

69.7 (65.9, 73.6)

< 0.001

12–13

79.7 (78.9, 80.5)

69.4 (65.2, 73.5)

< 0.001

78.4 (77.5, 79.3)

67.4 (64.2, 70.7)

< 0.001

14–15

81.5 (80.4, 82.6)

68.3 (62.5, 74.0)

< 0.001

78.0 (76.7, 79.2)

64.8 (59.4, 70.2)

< 0.001

16–17

81.1 (79.7, 82.6)

60.0 (50.3, 69.7)

< 0.001

75.7 (74.2, 77.1)

63.5 (58.7, 68.3)

< 0.001

Social functioning

10–11

83.0 (82.0, 84.0)

77.43 (73.4, 81.3)

0.007

81.4 (80.4, 82.5)

77.2 (73.1, 81.2)

0.041

12–13

85.1 (84.2, 86.0)

79.1 (74.4, 83.7)

0.013

84.3 (83.4, 85.2)

81.5 (78.2, 84.7)

0.10*

14–15

84.3 (82.9, 85.7)

71.5 (63.0, 80.0)

0.003

81.3 (80.0, 82.6)

75.2 (69.7, 80.6)

0.036

16–17

87.9 (86.2, 89.6)

80.7 (74.6, 86.9)

0.027

84.8 (83.2, 86.4)

81.8 (76.2, 87.5)

0.045

Psychosocial health summary score

10–11

78.4 (77.6, 79.1)

70.4 (66.9, 74.0)

< 0.001

79.2 (78.4, 79.9)

74.2 (70.8, 77.6)

< 0.004

12–13

79.8 (79.1, 80.5)

71.0 (67.1, 74.8)

< 0.001

80.7 (79.9, 81.4)

74.5 (72.0, 77.2)

< 0.001

14–15

79.4 (78.4, 80.4)

68.0 (62.3, 73.8)

< 0.001

78.7 (77.5, 79.8)

69.4 (64.8, 74.1)

< 0.001

16–17

81.6 (80.2, 82.9)

67.2 (60.9, 73.6)

< 0.001

79.1 (77.8, 80.5)

72.0 (67.1, 76.8)

0.007

Total score

10–11

79.8 (79.0, 80.6)

71.7 (68.3, 75.0)

< 0.001

80.0 (79.2, 80.8)

74.9 (71.2, 78.6)

0.008

12–13

81.7 (81.0, 82.4)

73.1 (69.6, 76.6)

< 0.001

82.2 (81.5, 83.0)

75.3 (72.7, 77.9)

< 0.001

14–15

81.0 (79.8, 82.1)

68.0 (61.4, 74.6)

< 0.001

79.9 (78.8, 81.1)

70.3 (65.5, 75.0)

< 0.001

16–17

82.8 (81.4, 84.2)

71.1 (65.9, 76.3)

< 0.001

80.4 (79.1, 81.8)

73.2 (69.1, 77.3)

0.001