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Table 3 CH-QoL sensitivity to change for the patients with cluster headache who underwent ventral tegmental area deep brain stimulation (VTA-DBS).

From: The sensitivity to change of the cluster headache quality of life scale assessed before and after deep brain stimulation of the ventral tegmental area

CH-QoL subscale

Baseline (SD)

Post (SD)

Mean Diff

Paired t-test (95 % CI)

p-values

Cohen’s d

SRM

ADL Restriction

29.4 (4.8)

24.9 (9.2)

-4.5

-2.28 (-6.8, -0.2)

0.01*

-0.7

-0.7

Mood & interpersonal relations

26.5 (9.1)

24.4 (9.9)

-2.1

-1.52 (-5.4, 0.9)

0.14

-0.3

-0.4

Pain and anxiety

6.2 (1.5)

6.2 (2.3)

0.0

-1.02 (-1.4, 0.47)

0.30

-0.3

-0.3

Lack of vitality

15.5 (2.2)

14.8 (3.2)

-0.7

-1.08 (-2.6,0.9)

0.29

-0.3

-0.2

CH-QoL total score

77.6 (14.5)

70.3 (21.6)

-7.3

− 2.05 (− 14.4,0.3)

0.03*

-0.6

-0.5

Clinical Outcome

       

HAL+

987.1 (649.5)

553.45 (761.7)

-443.7

-2.60 (-858.5, -102)

0.01

-0.6

-0.6

  1. ADL activities of daily living, CH-QoL cluster headache quality of life scale, CI confidence interval, HAL headache load (composite of frequency, severity and duration of cluster headache episodes), Mean DIFF = Mean Post – Mean Baseline, SD standard deviation, SRM standard mean response,* significant p-values + cluster headache patients