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Table 1 Baseline demographic and clinical profiles in HFEM and CM patients

From: Galcanezumab for the prevention of high frequency episodic and chronic migraine in real life in Italy: a multicenter prospective cohort study (the GARLIT study)

 

HFEM (n = 33)

CM (n = 130)

p

Age (years. Mean. SD)

44.2 (11.7)

47.9 (16.7)

.127

Sex (%. Females)

82.4

80.6

1.000

BMI (kg/m2. median. IQr)

23.20 (4.25)

23.00 (3.68)

.487

Comorbidities (%)

Psychiatric

18.8

20.5

1.000

Gastrointestinal

7.1

14.8

.367

Vascular

0

6.1

.345

Hormonal

14.3

10.5

.521

Cancer

10.7

1.8

.053

Respiratory

3.6

1.8

.485

Diabetes

0

2.7

1.000

Hypertension

7.1

15.8

.365

Immuno- rheumatologic

3.6

4.4

1.000

Overweight

36.4

28.6

.468

Other

17.9

12.1

.531

MO (%)

20.6

85.3

<.001

Disease history (years. Median. IQr)

26 (22)

30 (13)

.117

Pain characteristics (%)

  

.033

throbbing

46.9

70.7

 

dull

50.0

28.5

 

other

3.1

0.8

 

Dopaminergic features (%)

57.1

64.0

.519

Allodynia (%)

43.8

67.5

.023

Unilateral cranial autonomic features (%)

46.4

48.2

.863

Temporal artery hyperpulsatility (%)

11.5

23.1

.274

Number of failed preventives (median. IQr. [min-max])

4 (3) [3–12]

5 (3) [3–12]

.008

Triptan efficacy degree (median. IQr)

2 (1)

1 (1)

<.001

NRS (median. IQr)

7 (1)

8 (1)

.038

MMDs (median. IQr)

11 (3)

20 (10)

<.001

MHDs (median. IQr)

11 (4)

21 (12)

<.001

MPI (median. IQr)

12 (5)

20 (15)

<.001

HIT-6 (median. IQr)

66 (8)

68 (8)

.114

MIDAS (median. IQr)

30 (29)

72 (60)

<.001

  1. HFEM high frequency episodic migraine, CM chronic migraine, BMI body mass index, MO medication overuse, NRS Numeric Rating Scale, MMDs monthly migraine days, MHDs monthly headache days, MPI monthly pain-killer intake, HIT-6 headache impact test, MIDAS migraine disability assessment scale