Administrative prevalence and incidence, characteristics and prescription patterns of patients with migraine in Germany: a retrospective claims data analysis

Table 3 Prescribed in- and off-label (Group 2) preventive medications for patients with migraine in the German Company Sickness Fund Database 2016

Class Preventive medication	Percentage of all prescriptions for preventive medications
Beta-blockers	53.8
Metoprolol	29.6
Bisoprolol	21.0
Propranolol	3.2
ACEis and ARAs	22.4
ARAs (‘sartans’)	20.1
Lisinopril	2.3
Antidepressants	16.0
Amitriptyline	9.5
Opipramol	6.5
Anticonvulsants	5.7
Topiramate	4.2
Valproic acid	1.5
Muscle relaxants	0.8
Onabotulinum toxin A^a	0.8
Calcium channel blockers	0.8
Flunarizine	0.8
Magnesium compounds	0.5

Data shown are for prescribed Group 2 preventive medications (all preventive medications according to the German guideline for migraine [8])
^aPrescriptions for the Allergan brand of onabotulinum toxin A only were included
ACEi angiotensin-converting enzyme inhibitor; ARA angiotensin II receptor antagonist

ISSN: 1129-2377