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Table 6 Acute migraine treatment, second step: triptans available in Denmark (stated by date of marketing)

From: Reference programme: Diagnosis and treatment of headache disorders and facial pain. Danish Headache Society, 2nd Edition, 2012

Triptan

Formulation

Comments

Sumatriptan

Tablets 50 and 100 mg

 

Nasal spray 10 and 20 mg

Suppositories 25 mg

Subcutaneous injection 6 mg

Zolmitriptan

Tablets 2.5 and 5 mg

Naratriptan

Tablets 2.5 mg

Less effective than sumatriptan

Rizatriptan

Tablets 10 mg

5 mg when used in conjunction with propranolol treatment

Almotriptan

Tablets 12.5 mg

Possibly less side effects than sumatriptan

Eletriptan

Tablets 40

80 mg allowed if 40 mg is ineffective

Frovatriptan

Tablets 2.5 mg

Possibly less effective, fewer side effects and a longer duration of effect than sumatriptan

  1. An additional dose may be administered after a minimum of 2 h if the first dose has an effect and the headache returns. Generally, a maximum of two doses per day